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The role of air pollution on ST-elevation myocardial infarction: a narrative mini review

    Mohammad Amin Shahrbaf

    Cardiovascular Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran

    Authors contributed equally

    Search for more papers by this author

    ,
    Mohammad Parsa Mahjoob

    Cardiovascular Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran

    Authors contributed equally

    Search for more papers by this author

    ,
    Isa Khaheshi

    *Author for correspondence: Tel.: +98 212 208 3106;

    E-mail Address: isa.khaheshi@gmail.com

    Cardiovascular Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran

    Modarres Hospital, Kaj square, Sa'adat Abad Ave, Tehran, Iran, 1998734383

    ,
    Mohammad Ali Akbarzadeh

    Cardiovascular Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran

    ,
    Elham Barkhordari

    Cardiovascular Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran

    ,
    Mohammadreza Naderian

    Non-Communicable Diseases Research Center, Endocrinology & Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran

    &
    Farbod Zahed Tajrishi

    Faculty of Medicine, Babol University of Medical Sciences, Babol, Iran

    Published Online:https://doi.org/10.2217/fca-2017-0078

    ST-elevation myocardial infarction (STEMI) is one of the potential causes of death worldwide. In spite of substantial advances in its diagnosis and treatment, STEMI is still considered as a major public health dilemma in developed and particularly developing countries. One of the triggering factors of STEMI is supposed to be air pollutants like gaseous pollutants including, sulfur dioxide, nitric dioxide, carbon monoxide, ozone and particulate matters (PM) including, PM under 2.5 µm (PM2.5) and PM under 10 µm (PM10). Air pollution can trigger STEMI with various mechanisms such as increasing inflammatory factors and changing the heart rate or blood viscosity. In this article, we aimed to explore research in the field and discuss the relationship between air pollution and STEMI.

    Papers of special note have been highlighted as: • of interest; •• of considerable interest

    References

    • 1 Ahmadi A, Soori H, Mehrabi Y, Etemad K, Samavat I, Khaledlfar A. Incidence of acute myocardial infarction in Islamic Republic of Iran: a study using national registry data in 2012. E. Mediterr. Health J. 21(1), 5–12 (2015).
    • 2 Ahmadi A, Soori H, Sajjadi H. Modeling of in hospital mortality determinants in myocardial infarction patients, with and without type 2 diabetes, undergoing pharmaco-invasive strategy: the first national report using two approaches in Iran. Diabetes Res. Clin. Pr. 108(2), 216–222 (2015).
    • 3 Harper K, Armelagos G. The changing disease-scape in the third epidemiological transition. Int. J. Environ. Pollut. 7(2), 675–697 (2010).
    • 4 Pope CA, Muhlestein JB, Anderson JL et al. Short-term exposure to fine particulate matter air pollution is preferentially associated with the risk of ST-segment elevation acute coronary events. J. Am. Heart Assoc. 4(12), e002506 (2015). • Explains the association between air pollution and myocardial infarction (MI).
    • 5 Tonne C, Wilkinson P. Long-term exposure to air pollution is associated with survival following acute coronary syndrome. Eur. Heart J. 34(17), 1306–1311 (2013). • Explains the association between air pollution and MI.
    • 6 Brook RD, Franklin B, Cascio W et al. Air pollution and cardiovascular disease. Circulation 109(21), 2655–2671 (2004). • Explains the association between air pollution and MI.
    • 7 Crouse DL, Peters PA, Van Donkelaar A et al. Risk of nonaccidental and cardiovascular mortality in relation to long-term exposure to low concentrations of fine particulate matter: a Canadian national-level cohort study. Environ. Health Persp. 120(5), 708 (2012).
    • 8 Miller KA, Siscovick DS, Sheppard L et al. Long-term exposure to air pollution and incidence of cardiovascular events in women. N. Engl. J. Med. 2007(356), 447–458 (2007).
    • 9 De Paula Santos U, Braga ALF, Giorgi DMA et al. Effects of air pollution on blood pressure and heart rate variability: a panel study of vehicular traffic controllers in the city of Sao Paulo, Brazil. Eur. Heart J. 26(2), 193–200 (2004).
    • 10 Devlin R, Ghio A, Kehrl H, Sanders G, Cascio W. Elderly humans exposed to concentrated air pollution particles have decreased heart rate variability. Eur. Respir. J. Suppl. 21(40 Suppl.), s76–s80 (2003).
    • 11 Ibald-Mulli A, Stieber J, Wichmann H-E, Koenig W, Peters A. Effects of air pollution on blood pressure: a population-based approach. Am. J. Public Health 91(4), 571 (2001).
    • 12 Pope CA, Verrier RL, Lovett EG et al. Heart rate variability associated with particulate air pollution. Am. Heart J. 138(5), 890–899 (1999).
    • 13 WHO. The world health report 2002: reducing risks, promoting healthy life (2002). www.who.int/whr/2002/en/.
    • 14 Brunekreef B. Air pollution and life expectancy: is there a relation? Occup. Environ. Med. 54(11), 781 (1997).
    • 15 Newby DE, Mannucci PM, Tell GS et al. Expert position paper on air pollution and cardiovascular disease. Eur. Heart J. 36(2), 83–93 (2014).
    • 16 Cesaroni G, Forastiere F, Stafoggia M et al. Long term exposure to ambient air pollution and incidence of acute coronary events: prospective cohort study and meta-analysis in 11 European cohorts from the ESCAPE Project. BMJ Open 348, f7412 (2014).
    • 17 Mustafić H, Jabre P, Caussin C et al. Main air pollutants and myocardial infarction: a systematic review and meta-analysis. JAMA 307(7), 713–721 (2012).
    • 18 Nuvolone D, Balzi D, Chini M, Scala D, Giovannini F, Barchielli A. Short-term association between ambient air pollution and risk of hospitalization for acute myocardial infarction: results of the cardiovascular risk and air pollution in Tuscany (RISCAT) study. Am. J. Epidemiol. 174(1), 63–71 (2011).
    • 19 Bhaskaran K, Hajat S, Haines A, Herrett E, Wilkinson P, Smeeth L. The effects of air pollution on the incidence of myocardial infarction: a systematic review. Heart 95(21), 1746–1759 (2009).
    • 20 Cadum E, Berti G, Biggeri A, Bisanti L, Faustini A, Forastiere F. The results of EpiAir and the national and international literature. Epidemiol. Prev. 33(6 Suppl. 1), 113–119 (2009).
    • 21 Goggins WB, Chan EY, Yang C-Y. Weather, pollution and acute myocardial infarction in Hong Kong and Taiwan. Int. J. Cardiol. 168(1), 243–249 (2013).
    • 22 Maitre A, Bonneterre V, Huillard L, Sabatier P, De Gaudemaris R. Impact of urban atmospheric pollution on coronary disease. Eur. Heart J. 27(19), 2275–2284 (2006).
    • 23 Nuvolone D, Balzi D, Pepe P et al. Ozone short-term exposure and acute coronary events: a multicities study in Tuscany (Italy). Environ. Res. 126, 17–23 (2013).
    • 24 Gardner B, Ling F, Hopke PK et al. Ambient fine particulate air pollution triggers ST-elevation myocardial infarction, but not non-ST elevation myocardial infarction: a case-crossover study. Part. Fibre Toxicol. 11(1), 1 (2014).
    • 25 Manari A, Albiero R, De Servi S. High-risk non-ST-segment elevation myocardial infarction versus ST-segment elevation myocardial infarction: same behaviour and outcome? J. Cardiovasc. Med. 10, S13–S16 (2009).
    • 26 Polonski L, Gasior M, Gierlotka M et al. A comparison of ST elevation versus non-ST elevation myocardial infarction outcomes in a large registry database: are non-ST myocardial infarctions associated with worse long-term prognoses? Int. J. Cardiol. 152(1), 70–77 (2011).
    • 27 Pope CA 3rd, Hansen ML, Long RW et al. Ambient particulate air pollution, heart rate variability and blood markers of inflammation in a panel of elderly subjects. Environ. Health Persp. 112(3), 339 (2004).
    • 28 Bräuner EV, Møller P, Barregard L et al. Exposure to ambient concentrations of particulate air pollution does not influence vascular function or inflammatory pathways in young healthy individuals. Part. Fibre Toxicol. 5(1), 13 (2008).
    • 29 Mills NL, Törnqvist H, Gonzalez MC et al. Ischemic and thrombotic effects of dilute diesel-exhaust inhalation in men with coronary heart disease. N. Engl. J. Med. 357(11), 1075–1082 (2007).
    • 30 Dockery DW, Luttmann-Gibson H, Rich DQ et al. Association of air pollution with increased incidence of ventricular tachyarrhythmias recorded by implanted cardioverter defibrillators. Environ. Health Persp. 113(6), 670 (2005).
    • 31 Peters A, Döring A, Wichmann H-E, Koenig W. Increased plasma viscosity during an air pollution episode: a link to mortality? Lancet 349(9065), 1582–1587 (1997). • Explains the association between air pollutants and physiological changes in human body.
    • 32 Bouthillier L, Vincent R, Goegan P et al. Acute effects of inhaled urban particles and ozone: lung morphology, macrophage activity and plasma endothelin-1. Am. J. Pathol. 153(6), 1873–1884 (1998).
    • 33 Brook RD, Brook JR, Urch B, Vincent R, Rajagopalan S, Silverman F. Inhalation of fine particulate air pollution and ozone causes acute arterial vasoconstriction in healthy adults. Circulation 105(13), 1534–1536 (2002).
    • 34 Zanobetti A, Canner MJ, Stone PH et al. Ambient pollution and blood pressure in cardiac rehabilitation patients. Circulation 110(15), 2184–2189 (2004). • Explains the association between air pollution and cardiovascular risk factors.
    • 35 Zanobetti A, Schwartz J. The effect of particulate air pollution on emergency admissions for myocardial infarction: a multicity case-crossover analysis. Environ. Health Persp. 113(8), 978–982 (2005).
    • 36 Linn WS, Szlachcic Y, Gong H Jr, Kinney PL, Berhane KT. Air pollution and daily hospital admissions in metropolitan Los Angeles. Environ. Health Persp. 108(5), 427–434 (2000).
    • 37 Argacha J, Collart P, Wauters A et al. Air pollution and ST-elevation myocardial infarction: a case-crossover study of the Belgian STEMI registry 2009–2013. Int. J. Cardiol. 223, 300–305 (2016).
    • 38 Rich DQ, Kipen HM, Zhang J et al. Triggering of transmural infarctions, but not nontransmural infarctions, by ambient fine particles. Environ. Health Persp. 118(9), 1229 (2010).
    • 39 Caussin C, Escolano S, Mustafic H et al. Short-term exposure to environmental parameters and onset of ST elevation myocardial infarction. The CARDIO-ARSIF registry. Int. J. Toxicol. 183, 17–23 (2015).
    • 40 Butland BK, Atkinson RW, Milojevic A et al. Myocardial infarction, ST-elevation and non-ST-elevation myocardial infarction and modeled daily pollution concentrations: a case-crossover analysis of MINAP data. Open Heart 3(2), e000429 (2016).
    • 41 Akbarzadeh MA, Khaheshi I, Sharifi A et al. The association between exposure to air pollutants including PM 10, PM 2.5, ozone, carbon monoxide, sulfur dioxide and nitrogen dioxide concentration and the relative risk of developing STEMI: a case-crossover design. Environ. Res. 161, 299–303 (2018). • Explains the association between different air pollutant materials and MI.